On-resin peptide macrocyclization using thiol–ene click chemistry
نویسندگان
چکیده
منابع مشابه
On-resin peptide macrocyclization using thiol-ene click chemistry.
A versatile and rapid synthetic strategy has been developed for the on-resin cyclization of peptides using thiol-ene photochemistry. This unique method exploits the thiol group of natural cysteine amino acids and allows for various alkenes to be incorporated orthogonal to the peptide backbone.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2010
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c001375g